Dendritic cells (DCs) refer to antigen-presenting cells of the mammalian immune system. The major job of the dendritic cells is to process antigen material and present it on the cell surface to the T cells of the immune system. They serve as messengers among the adaptive and innate immune systems. Dendritic cells are found in those tissues that come contact with the external environment, such as the skin and the inner lining of the stomach, nose, intestines and lungs. They can also be detected in the blood in an immature form. Dendritic cells are obtained from hematopoietic bone marrow progenitor cells, which first develop into immature dendritic cells and communicate continuously with other cells in the body. The communication can occur in the form of direct cell-cell contact on the basis of interaction between cell-surface proteins. This book aims to understand the immunobiology of dendritic cells. The topics included herein are of utmost significance and bound to provide incredible insights to the readers. Researchers and students engaged in the study of dendritic cells will be assisted by this book.