The sudden death of her brother Jim, and the subsequent discovery of a half-sister living in Tuscany, up end Catherine (Cat) Emerson's tranquil life. Since Cat refuses to fly-even in a post-pandemic world- her Tuscan sister Luna Bianchi and Nico, Luna's soon-to-be adopted son, travel to Amelia Island, Florida to join Cat. On the flight, Luna and Nico meet Sam Lawrence who's a dead-ringer for Cat's high school boyfriend. A romance blossoms between Cat and Sam.

After Jim's passing, his coworker Rodney approaches Cat about possible illegalities at the company her brother co-owned. When Rodney is murdered, Cat and her friend Lisa become embroiled in the mystery. Lisa continues to investigate Rodney's death when Cat takes a cruise ship from Florida to Italy to visit her sister. During Cat, Luna, and Nico's tour of Sicily, Luna is called back to her home in Siena by the police. A day later, Luna vanishes.

Will Cat face her greatest fear and fly from Sicily to Tuscany to find her sister before it's too late?